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Dye–Protein
Compounds and compositions comprising fluorophores for use in visualization and purification or manipulation
The application discloses a compound having a moiety that is either an affinity tag-containing moiety or a protein-manipulation moiety, …
Luke D. Lavis
,
Pratik Kumar
,
Carla Nicolini
,
Jonathan B. Grimm
Last updated on Feb 17, 2025
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DOI
Google Patents
Optimizing multifunctional fluorescent ligands for intracellular labeling
Enzyme-based self-labeling tags enable covalent attachment of synthetic molecules to proteins inside living cells. A frontier of this …
Pratik Kumar
,
Jason D. Vevea
,
Ariana N. Tkachuk
,
Kirby Campbell
,
Emma T. Watson
,
Anthony X. Ayala
,
Jonathan B. Grimm
,
Edwin R. Chapman
,
David J. Solecki
,
Luke D. Lavis
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DOI
preLights
bioRxiv
Janelia News
Biotin-free proximity labeling
Compounds useful for biotin-free proximity labeling are provided. Also provided are methods for biotin-free labeling of biomolecules in …
Shu-Hsien Sheu
,
Pratik Kumar
,
Luke D. Lavis
Last updated on Feb 17, 2025
Single-cell synaptome mapping of endogenous protein subpopulations in mammalian brain
Motokazu Uchigashima
,
Risa Iguchi
,
Kazuma Fujii
,
Kaito Shiku
,
Pratik Kumar
,
Xinyi Liu
,
Mari Isogai
,
Chiaki Hoshino1
,
Manabu Abe
,
Motohiro Nozumi
,
Yosuke Okamura
,
Michihiro Igarashi
,
Kenji Sakimura
,
Ryoma Bise
,
Luke Lavis
,
Takayasu Mikuni
Transforming chemigenetic bimolecular fluorescence complementation systems into chemical dimerizers using chemistry
Chemigenetic tags are versatile labels for fluorescence microscopy that combine some of the advantages of genetically encoded tags with …
Pratik Kumar
,
Alina Gutu
,
Amelia Waring
,
Timothy A. Brown
,
Luke D. Lavis
,
Alison G. Tebo
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DOI
bioRxiv
Melding Synthetic Molecules and Genetically Encoded Proteins to Forge New Tools for Neuroscience
Unraveling the complexity of the brain requires sophisticated methods to probe and perturb neurobiological processes with high …
Pratik Kumar
,
Luke D. Lavis
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