Rhodamine

Compounds and compositions comprising fluorophores for use in visualization and purification or manipulation

The application discloses a compound having a moiety that is either an affinity tag-containing moiety or a protein-manipulation moiety, …

Luke D. Lavis, Pratik Kumar, Carla Nicolini, Jonathan B. Grimm

Last updated on Feb 17, 2025

Optimizing multifunctional fluorescent ligands for intracellular labeling

Enzyme-based self-labeling tags enable covalent attachment of synthetic molecules to proteins inside living cells. A frontier of this …

Pratik Kumar, Jason D. Vevea, Ariana N. Tkachuk, Kirby Campbell, Emma T. Watson, Anthony X. Ayala, Jonathan B. Grimm, Edwin R. Chapman, David J. Solecki, Luke D. Lavis

Single-cell synaptome mapping of endogenous protein subpopulations in mammalian brain

Motokazu Uchigashima, Risa Iguchi, Kazuma Fujii, Kaito Shiku, Pratik Kumar, Xinyi Liu, Mari Isogai, Chiaki Hoshino1, Manabu Abe, Motohiro Nozumi, Yosuke Okamura, Michihiro Igarashi, Kenji Sakimura, Ryoma Bise, Luke Lavis, Takayasu Mikuni

Melding Synthetic Molecules and Genetically Encoded Proteins to Forge New Tools for Neuroscience

Unraveling the complexity of the brain requires sophisticated methods to probe and perturb neurobiological processes with high …

Pratik Kumar, Luke D. Lavis

Melding Synthetic Molecules and Genetically Encoded Proteins to Forge New Tools for Neuroscience